Articles by tag: biology

What is differential analysis, anyway?

Differential analysis using sequencing data is, at its heart, a very simple idea that involves a lot of complicated statistics. It makes explaining the simple idea to newcomers in bioinformatics very difficult. Here, I want to break down the motivation behind differential analysis and explain where the complicated statistics come from.

Please, show your work

How incomprehensible machine learning models answer questions without providing the solutions we desire.

Well-defined biology

Why are definitions important, and what makes them "good"? Here I focus on is the topic of definitions being "good" and "well-defined" and how to ask good quantitative questions in biology.

Now is an exciting time for mathematicians in the biological sciences

There are many reasons to be excited about scientific progress in the biological sciences, especially if you're a mathematician of almost any kind.